Epidemiologi ved blandet bindevevsykdom, mixed connective tissue disease (MCTD) hos barn
نویسندگان
چکیده
منابع مشابه
Vascular disease in mixed connective tissue disease (MCTD).
Sharp et al first described mixed connective tissue disease (MCTD)in 1972 as a distinct entity of connective tissue disease (1). MCTDis a disease entity characterized by overlap symptoms of systemic lupus erythematosus (SLE), systemic sclerosis (SSc) and polymyositis/dermatomyositis (PM/DM), as well as by the presence of antibody to U1RNRHowever, it has been suggested that rather than being reg...
متن کاملExercise limitation in juvenile onset Mixed Connective Tissue Disease (MCTD)
Results VO2peak was significantly lower in patients with MCTD compared to the VO2peak of healthy subjects (z-score -1.9, p = 0.008). The strength of the proximal muscles (hip flexors, shoulder abductors, knee extensors) of the patients was significantly lower than the controls, whereas the strength of the distal muscles (dorsal flexors of the foot and grip strength) was rather similar. No clini...
متن کاملEvaluation of interstitial lung disease in mixed connective tissue disease (MCTD).
OBJECTIVE Interstitial lung disease (ILD) may be a characteristic, often serious, manifestation of mixed connective tissue disease (MCTD). In this retrospective study, the frequency and clinical picture of ILD were determined in patients with MCTD using two diagnostic tests: high-resolution computed tomography (HRCT) and inhaled aerosol clearance times of (99m)Tc-labelled diethylene-triamine pe...
متن کاملTocilizumab for the treatment of refractory pediatric mixed connective tissue disease (MCTD), in two patients
Introduction Mixed Connective Tissue Disease (MCTD) is a rare autoimmune disease of unknown origin. The diagnosis is suggested when there are overlaping symptoms of lupus, scleroderma and dermatomyositis. Kasukawa criteria are the most commonly used in pediatrics. Treatment should be tailored to the clinical symptoms but no specific recommendation regarding the therapeutic management has been e...
متن کامل[Mixed connective tissue disease].
Mixed connective tissue disease deserves to be a distinct disease entity due to the persistent citation of this disease in the literature since the original description by Sharp in 1972, in spite of the presence of several criticisms against the independency of this disease. The characteristic features of mixed connective tissue disease are: 1) the presence of anti-U1snRNP antibody with high ti...
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ژورنال
عنوان ژورنال: Norsk Epidemiologi
سال: 2009
ISSN: 0803-2491
DOI: 10.5324/nje.v18i1.79